In this article, we present that conolidine, a all-natural analgesic alkaloid used in conventional Chinese medication, targets ACKR3, thus offering supplemental evidence of a correlation among ACKR3 and suffering modulation and opening choice therapeutic avenues with the therapy of Continual soreness. Tabernaemontana divaricata Conolidine is an indole alkaloid. Preliminary https://jimt294sag0.oneworldwiki.com/user