Contraindicated (1)pentobarbital will reduce the level or effect of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Use of naloxegol with strong CYP3A4 inducers is just not suggested pentobarbital will lower the level or impact of suvorexant by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe. Sturdy CYP3A4 inducers may ... https://rogera962ijq3.mycoolwiki.com/user